Isothermal amplification system based on template-dependent extension.

نویسندگان

  • Hui Zhou
  • Su-Jin Xie
  • Song-Bai Zhang
  • Guo-Li Shen
  • Ru-Qin Yu
  • Zai-Sheng Wu
چکیده

A novel template-dependent extension based isothermal amplification (TEIA) system with high single-base discrimination capability is developed, where the interference caused by non-specific reaction in isothermal strand displacement amplification (SDA) technique is substantially avoided via using a functionalized template probe, showing potential value in the development and application of SDA based detection devices.

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عنوان ژورنال:
  • Chemical communications

دوره 49 24  شماره 

صفحات  -

تاریخ انتشار 2013